Journal Articles

2019/In Press

35. Yang B, Lu Y, Um C, O’Connell GD. Relative Nucleus Pulposus Area and Position Alters Disc Joint Mechanics. J Biomech Eng. 141(5): 051004, 2019.

34. Yang B, O’Connell GD. GAG content, fiber stiffness, and fiber angle affect swelling-based residual stress in the intact annulus fibrosus. BMMB 18(3): 617-630, 2019.

33. Werbner B, Spack K, O’Connell GD. Bovine Annulus Fibrosus Hydration Affects Rate-Dependent Failure Mechanics Under Monotonic Tension. J Biomech. Jan; 89: 34-39, 2019.


32. Pendleton MM, Sadoughi S, Li A, O’Connell GD, Alwood JS, Keaveny TM. High-Precision Method for Cyclic Loading of Small Animal Vertebrae to Assess Bone Quality. Bone Reports 9(12): 165-172, 2018.

31. López-Marcial GR, Zeng AY, Osuna C, García JM*, O’Connell GD*. Characterization of Printable Bioinks for Cartilage Tissue Engineering. * co-corresponding authors. ACS Biomaterials 4(10):3610-3616, 2018.

30. Bezci SE, Eleswarapu A, Klineberg EO, O’Connell GD. Contribution of facets, axial compression, and composition on human lumbar discs in torsion. JOR; 36(8): 2266-2273, 2018.

29. Yang B, O’Connell GD. Swelling of fiber-reinforced soft tissues is affected by fiber orientation, fiber stiffness, and lamella structure. JBMMB. Jun; 82: 320-328, 2018. PMID: 29653381.

28. Ford AC, Chui WF, Zeng AY, Nandy A, Liebenberg MA, Carraro C, Kazakia G, Alliston T, O’Connell GD. A Modular Approach to Creating Large Engineered Cartilage Surfaces. J Biomech.; Jan.; 67: 177-183, 2018.

27. Bezci SE, O’Connell GD. Osmotic pressure alters time-dependent recovery behavior of the intervertebral disc. Spine. Mar 15;43(6):E334-E340, 2018.

26. Bezci SE, Klineberg EO, O’Connell GD. Effects of Axial Compression and Rotation Angle on Intervertebral Disc Mechanics in Torsion. J Mech Beh Biomed Materials. Jan.; 77:353-359, 2018.


25. Yang B, O’Connell GD. Effect of collagen fiber orientation on intervertebral disc torsion mechanics. Biomech and Modeling in Mechanobiology. Dec.; 16(6): 2005-15, 2017.

24. O’Connell GD, Garcia J, Jamali A. 3D Bioprinting: New directions in articular cartilage tissue engineering.ACS Biomaterials Science & Engineering. 3(11); 2657-2668, Nov., 2017.

23. Werbner BN, Zhou M, O’Connell GD. A Novel Method for Repeatable Failure Testing of Annulus Fibrosus. J Biomech Eng. Nov. 1; 139(11), 2017.


22. Stannard JT, Edamura K, Stoker A, O’Connell GD, Kuroki K, Hung CT, Choma TJ, Kuhns CA, Jefferies JT, Reinsel T, Cook, JL. Development of a Whole Organ Culture Model for Intervertebral Disc Disease. Journal of Translational Orthopaedics, April; 5:1-5, 2016.

21. Nover AB, Hou GY, Han Y, Wang S, O’Connell GD, Ateshian GA, Konofagou EE, Hung CT. High Intensity Focused Ultrasound as a Tool for Tissue Engineering: Application to Cartilage. Med Eng Phys, Feb; 38(2), 192-198, 2016.


20. O’Connell GD, Leach JK, Kleinberg E. Tissue engineering a biological repair strategy for lumbar disc herniation. BioResearch, Nov 1;4(1):431-45. 2015.

19. Ponnurangam S, O’Connell GD, Hung CT, and Somasundaran P. Biocompatibility of Polysebacic Anhydride Microparticles with Chondrocytes in Engineered Cartilage. Colloids and Surfaces B: Biointerfaces, Dec 1;136:207-13, 2015.

18. Bezci SE, Nandy A, O’Connell GD. Effect of hydration on healthy intervertebral disc mechanical stiffness. Journal of Biomechanical Engineering, Oct 1; 137(10), 2015. Author copy.

17. O’Connell GD, Tan AR, Palmer G, Cui V, Bulinski JC, Cook JL, Attur M, Abramson SB, Ateshian GA, Hung CT. Human chondrocyte migration behavior to guide the development of engineered cartilage. Journal of Tissue Engineering and Regenerative Medicine, 2015.

16. Tan AR, Alegre-Aguaron E, O’Connell GD, VandenBerg CD, Aaron RK, Vunjak-Novakovic G, Bulinski JC, Ateshian GA, Hung CT. Passage-Dependent Relationship between Mesenchymal Stem Cell Mobilization and Chondrogenic Potential. Osteoarthritis and Cartilage, 23:319-327, 2015.


15. O’Connell GD, Newman IB, Carapezza MA. Effect of long-term osmotic loading culture on matrix synthesis from intervertebral disc cells. BioResearch, Oct 1;3(5):242-9, 2014.

14. Ponnurangam S, O’Connell GD, Chernyshova I, Woods K, Somasundaran P, Hung CT. Ceria nanoparticles modulate development and interlukin response of chondrocyte-seeded hydrogel constructs. Tissue Engineering, Part A, Nov; 20(21-22):2908-19, 2014.

13. O’Connell GD, Nims R, Green J, Cigan A, Ateshian GA, Hung CT. Time and dose-dependent effects of chondroitnase ABC on growth of engineered cartilage. eCells and Materials Journal, Vol. 27: 312-320, 2014.


12. Kelly TAN, Roach BL, Weidner ZD, Mackenzie-Smith CR, O’Connell GD, Lima EG, Stoker AM, Cook JL, Ateshian GA, Hung CT. Tissue-engineered articular cartilage exhibits tension-compression nonlinearity reminiscent of the native cartilage. Journal of Biomechanics, Jul 26; 46(11): 1748-91, 2013.


11. O’Connell GD, Fong JV, Dunleavy N, Joff A, Ateshian GA, Hung CT. Trimethylamine N-Oxide found in shark cartilage improves collagen production in tissue-engineered cartilage. Journal of Orthopaedic Research, 30(12): 1898-905, 2012.

10. O’Connell GD, Lima EK, Bian L, Chahine NO, Albro MB, Cook JL Ateshian GA, Hung CT. Toward Engineering a Biological Joint Replacement. Invited review paper for the Journal of Knee Surgery; 25(3): 187-96, 2012.


9. Sampat S*, O’Connell GD, Fong JV, Augaron EA, Ateshian GA, Hung CT. Growth Factor Priming of Synovium Derived Stem Cells for Cartilage Tissue Engineering. Tissue Engineering Part A, 17(17-18): 2259-65, 2011. *These authors contributed equally to the study and manuscript.

8. O’Connell GD, Sen S, Elliott DM. Human Annulus Fibrosus Material Properties from Biaxial Testing and Constitutive Modeling are Altered with Degeneration. BMMB, 11(3-4): 493-503, 2011.

7. O’Connell GD, Malhotra NR, Vresilovic EJ, Elliott DM. The Effect of Nucleotomy and the Dependence on Degeneration of Human Intervertebral Disc Strain in Axial Compression. Spine, 36(21): 1765-71, 2011.

6. O’Connell GD, Jacobs NT, Sen S, Vresilovic EJ, Elliott DM. Axial Creep Loading and Unloaded Recovery of the Human Intervertebral Disc and the Effect of Degeneration. Journal of Mechanical Behavior and Biomedical Materials, 4(7): 933-42, 2011.

5. O’Connell GD, Vresilovic EJ, Elliott DM. Human Intervertebral Disc Internal Strain in Compression: The Effect of Disc Region, Loading Position, and Degeneration. Journal of Orthopaedic Research, 29(4): 547-55, 2011.


4. O’Connell GD, Guerin HL, Elliott DM. Theoretical and Uniaxial Experimental Evaluation of Human Annulus Fibrosus Degeneration. Journal of Biomechanical Engineering, 131(11): 111007, 2009.


3. O’Connell GD, Johannessen W, Vresilovic EJ, Elliott, D.M. Human Internal Disc Strains in Axial Compression Measured Non-Invasively Using Magnetic Resonance Imaging. Spine 32(25), 2860-68, 2007.

2. O’Connell GD, Vresilovic EJ, Elliott DM. Comparison of Animals Used in Disc Research to Human Lumbar Disc Geometry. Spine 32(3), 328-33, 2007.


1. Johannessen W, Cloyd JM, O’Connell GD, Vresilovic EJ, Elliott DM. Trans-Endplate Nucleotomy Increases Deformation and Creep Response in Axial Loading. Annals of Biomedical Engineering 34(4), 687-96, 2006.