Finite element models can provide predictions of stress and strain distributions in complex, fiber-reinforced tissues, which may be difficult or impossible to measure experimentally. Additionally, the models can also be used to guide experimental designs for studies that are time- or cost-intensive.
Our group has developed both tissue- and joint-level finite element models. The multiscale, structure-based tissue-level model is rigorously validated under multiple loading modalities, loading conditions, and boundary conditions, allowing us to simultaneously investigate both tissue- and subtissue-level mechanics. The model also has the potential to directly evaluate fiber-matrix interactions. The joint-level model is validated under multiple loading modalities and enables us to assess the effect of degeneration and combined multiaxial loading on disc mechanics.
If you are interested in the most recent finite element modeling research updates, please feel free to contact Minhao Zhou (minhao dot zhou at berkeley dot edu)